Hashimoto’s. Leaky Gut. Histamines. It’s All Connected -and Here’s Why You Still Feel Like Crap
If you’ve been treating your Hashimoto’s, eating clean, taking your supplements, and still feel exhausted, bloated, anxious, and inflamed - this post is for you.
Because what most thyroid patients (and even doctors) miss is the connection between Hashimoto’s, gut health, and histamine intolerance.
And if you’re not addressing this trifecta, you’re going to keep chasing symptoms.
📌 What is Histamine (and Why Should You Care About It with Hashimoto’s?)
Histamine is a natural chemical your body makes to support digestion, immune responses, and nervous system function.
You also get it from certain foods.
Normally, your body produces an enzyme called DAO (diamine oxidase) in your gut to break down histamine and keep it balanced. But when that system gets overloaded or compromised?
Histamine builds up and triggers a long list of “mystery” symptoms like:
Headaches
Hives, itchy skin
Heart palpitations
Anxiety or panic attacks
Bloating + gut issues
Runny nose, congestion
Insomnia
Brain fog
Menstrual irregularities
Sound familiar?
The problem is most of these symptoms overlap with Hashimoto’s - which means histamine intolerance often goes undetected.
📌 Why Histamine Intolerance is So Common with Hashimoto’s
Several things make people with Hashimoto’s more prone to histamine issues:
✅ Leaky Gut (Intestinal Permeability):
Common in autoimmune disease, it allows inflammatory molecules and histamine-releasing triggers into the bloodstream.
✅ Low DAO Enzyme Levels:
Hypothyroidism slows enzyme production - including DAO. When that’s low, histamine clearance slows down.
✅ Chronic Inflammation:
Ongoing immune activation in Hashimoto’s disrupts gut health, DAO production, and mast cell stability (which release histamine).
✅ Nutrient Deficiencies:
B6, vitamin C, copper, and magnesium deficiencies (common in thyroid disease) impair histamine breakdown.
📌 High-Histamine Foods to Watch for
Some foods are naturally high in histamine or trigger its release:
Aged cheeses
Fermented foods (kombucha, sauerkraut, yogurt)
Cured meats
Vinegars
Alcohol
Tomatoes, spinach, eggplant, avocado
Shellfish
Leftovers (histamine builds as food sits)
📌 How to Support Histamine Intolerance Naturally
✅ Heal the Gut First
Your gut is the gateway to immune regulation and inflammation control. My Gut & Inflammation Kickstart is the exact 30-day plan I use to calm gut inflammation and symptoms quickly.
✅ Limit High-Histamine Foods Temporarily
Trial a low-histamine plan for 2–4 weeks to see if symptoms calm.
✅ Boost DAO Production + Lower Inflammation
Add in nutrients and supplements to support your gut + histamine pathways:
Vitamin C
Vitamin B6
Magnesium
Omega-3s
Quercetin + Nettles (mast cell stabilizers)
I personally recommend Histamine Digest, Histamine Complete, or PureMax.
✅ Consider DAO Enzyme Supplements
Take before high-histamine meals if needed. Great for social situations, holidays, or when you just can’t avoid certain foods.
✅ Manage Stress
Cortisol spikes trigger histamine release. Daily walking, breathwork, nervous system resets - all part of my Healing Blueprint strategy.
📌 Final Thoughts
If you’ve been doing everything right and still feel stuck, it might not be your thyroid meds, your macros, or your workouts - it could be histamine intolerance flying under the radar.
And like everything else with Hashimoto’s, healing it starts with the gut.
If you’re ready to calm the inflammation, heal your gut lining, and tackle those lingering symptoms, grab my Gut & Inflammation Kickstart.
Or if you’re ready for a full, root-cause Healing Blueprint with private coaching support, apply to work with me here.
You don’t have to stay stuck. You just need to address the right systems.